Contents

Search

phosphoinositide-4-kinase

Function: - phosphorylation of phosphatidylinositol to yield PtdIns4P

Interactions

molecular events

Specific

phosphatidylinositol 4-kinase type 2-alpha (PI4K2A) phosphoinositide [PI] 3-phosphate 4-kinase phosphoinositide-4-kinase alpha (Ptdins-4-kinase alpha, PI4K-alpha, PI4KA) phosphoinositide-4-kinase beta (PI4Kbeta, NPIK, PI4K92, PIK4CB)

General

kinase or ATP-phosphotransferase phosphoprotein regulatory molecule

Properties

STATE: active state MOTIF: kinase domain MOTIF: ATP-binding site NAME: ATP-binding site Tyr phosphorylation site

References

  1. Nolan RD, Lapetina EG. Thrombin stimulates the production of a novel polyphosphoinositide in human platelets. J Biol Chem. 1990 Feb 15;265(5):2441-5. PMID: 2154447
  2. Alberts et al Molecular Biology of the Cell, 2nd ed. 1989, pg 702

Component-of

molecular complex