phosphoenolpyruvate carboxykinase

An enzyme obtained from Escherichia coli, yeast, & Trypanosoma brucei contains a putative ATP-binding site, presumably using ATP instead of GTP, but is NOT related to this form. In eukaryotes there are two isozymes: a cytoplasmic one (PEPCK1) & a mitochondrial one (PEPCK2)

Related

gluconeogenesis phosphoenolpyruvate carboxykinase [PEPCK] gene

Specific

phosphoenolpyruvate carboxykinase 1 (PCK1, cytosolic phosphoenolpyruvate carboxykinase) phosphoenolpyruvate carboxykinase 2 (mitochondrial phosphoenolpyruvate carboxykinase, PEPCK-M, PCK2, PEPCK2)

General

carboxy-lyase or decarboxylase gluconeogenic enzyme kinase or ATP-phosphotransferase

Properties

COMPARTMENT: cytoplasm mitochondria MOTIF: kinase domain MOTIF: GTP-binding site cysteine residue