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phosphatidylserine synthase 2 (Ptdser synthase 2, PSS-2, serine-exchange enzyme 2, PTDSS2, PSS2)
Function:
- catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine is replaced by L-serine
- inhibited by excess phosphatidylserine, but not by phosphatidylcholine or phosphatidylethanolamine
- phosphatidylserine biosynthesis
Structure: belongs to the phosphatidyl serine synthase family
Compartment: membrane
Related
phosphatidylserine synthase; serine-exchange enzyme 1; CDP diacylglycerol serine O-phosphatidyltransferase (PTDSS1)
General
glycoprotein
phosphotransferase
transmembrane 8 protein
Properties
SIZE: MW = 56 kD
entity length = 487 aa
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-62}
MOTIF: Ser phosphorylation site {S16}
transmembrane domain {63-83}
exoplasmic loop {84-96}
transmembrane domain {97-117}
cytoplasmic loop {118-126}
transmembrane domain {127-147}
exoplasmic loop {148-241}
MOTIF: N-glycosylation site {N181}
N-glycosylation site {N237}
transmembrane domain {242-262}
cytoplasmic loop {263-313}
transmembrane domain {314-334}
exoplasmic loop {335-335}
transmembrane domain {336-356}
cytoplasmic loop {357-376}
transmembrane domain {377-397}
exoplasmic loop {398-403}
transmembrane domain {404-424}
cytoplasmic domain {425-487}
Database Correlations
UniProt Q9BVG9
Pfam PF03034
References
UniProt :accession Q9BVG9