phosphatidylinositol N-acetylglucosaminyltransferase subunit Q; N-acetylglucosamyl transferase component GPI1; phosphatidylinositol-glycan biosynthesis class Q protein; PIG-Q (PIGQ GPI1)

Function: - part of the complex catalyzing transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the 1st step of GPI biosynthesis - glycolipid biosynthesis; GPI-anchor biosynthesis - associates with PIGA, PIGC, PIGH, PIGP & DPM2 Structure: belongs to the PIGQ family Compartment: membrane (putative) Alternative splicing: named isoforms=3

General

glycoprotein phosphatidylinositol-glycan biosynthesis protein (PIG-protein) transmembrane 5 protein

Properties

SIZE: entity length = 760 aa MW = 84 kD COMPARTMENT: endoplasmic reticulum MOTIF: transmembrane domain {278-298} transmembrane domain {349-371} transmembrane domain {378-400} transmembrane domain {446-468} transmembrane domain {475-497}

Database Correlations

OMIM 605754 UniProt Q9BRB3 Pfam PF05024 Entrez Gene 9091 Kegg hsa:9091 ENZYME 2.4.1.198

References

UniProt :accession Q9BRB3