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phenytoin teratogenesis
Pathology:
1) pulmonic valvular stenosis
2) aortic valvular stenosis
3) coarctation of the aorta
4) patent ductus arteriosus
2) hypertelorism
Clinical manifestations:
1) growth & mental deficiency
2) short phalanges
3) bowed upper lip
Related
phenytoin; diphenylhydantoin; PTN (Dilantin, Dephenylan, Antilepsin)
General
developmental disorder
References
Harrison's Principles of Internal Medicine, 13th ed.
Isselbacher et al (eds), McGraw-Hill Inc. NY, 1994, pg 1039