Search
peroxisomal 3,2-trans-enoyl-CoA isomerase; dodecenoyl-CoA isomerase; delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; DBI-related protein ;, DRS-1; hepatocellular carcinoma-associated antigen 88; NY-REN-1 antigen (PECI, DRS1, HCA88, ECI2)
Function:
- isomerizes both 3-cis & 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species
Structure:
- contains 1 ACB domain (acyl-CoA-binding domain)
Compartment: peroxisomal matrix
Expression: expressed in heart, skeletal muscle, liver
General
isomerase
Properties
SIZE: MW = 40 kD
entity length = 359 aa
COMPARTMENT: peroxisome
MOTIF: ACB {4-89}
ECH-like. {116-287}
microbody-targeting signal {357-359}
Database Correlations
OMIM 608024
UniProt O75521
PFAM correlations
ENZYME 5.3.3.8
References
UniProt :accession O75521