peptidylprolyl isomerase domain and WD repeat-containing protein 1 (PPWD1, KIAA0073)

Function: - component of spliceosome C complex - putative peptidylprolyl isomerase - accelerates the folding of proteins - catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. - may be involved in pre-mRNA splicing Structure: - belongs to the cyclophilin-type PPIase family, PPIL1 subfamily - contains 1 PPIase cyclophilin-type domain - contains 4 WD repeats

Properties

SIZE: MW = 74 kD entity length = 646 aa MOTIF: arginine-rich region {12-17} MOTIF: arginine residue (SEVERAL) WD repeat {88-126} WD repeat {131-170} WD repeat {221-260} WD repeat {278-319} active site SITE: 490-645

Database Correlations

UniProt Q96BP3 PFAM correlations ENZYME 5.2.1.8

References

UniProt :accession Q96BP3