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peptidoglycan recognition protein 1-beta (peptidoglycan recognition protein intermediate beta, PGRP-1-beta, PGLYRP1beta, peptidoglycan recognition protein 4, PGLYRP4, PGRPIB, SBBI67)
Function:
1) binds specifically to peptidoglycan & Gram-positive bacteria
2) role in innate immunity
Structure:
- belongs to the N-acetylmuramoyl-L-alanine amidase 2 family
Compartment: peripheral membrane
Expression:
- expressed in esophagus > tonsils, thymus
General
glycoprotein
membrane protein
Properties
SIZE: MW = 41 kD
entity length = 373 aa
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-17}
N-glycosylation site {N22}
N-glycosylation site {N39}
N-glycosylation site {N109}
N-glycosylation site {N145}
cysteine residue {C246}
MODIFICATION: cysteine residue {C252}
N-glycosylation site {N247}
cysteine residue {C252}
MODIFICATION: cysteine residue {C246}
Database Correlations
OMIM 608198
UniProt Q96LB8
Pfam PF01510
References
UniProt :accession Q96LB8