peptidoglycan recognition protein 1-alpha (peptidoglycan recognition protein intermediate alpha, peptidoglycan recognition protein 3, PGRP-1-alpha, PGLYRP1alpha, PGLYRP3, PGRPIA)

Function: 1) binds specifically to peptidoglycan & Gram-positive bacteria 2) role in innate immunity Structure: - belongs to the N-acetylmuramoyl-L-alanine amidase 2 family Compartment: peripheral membrane Expression: - expressed in esophagus, tonsils, thymus > stomach, descending colon, rectum, brain

General

glycoprotein membrane protein

Properties

SIZE: MW = 38 kD entity length = 341 aa COMPARTMENT: cellular membrane MOTIF: signal sequence {1-17} N-glycosylation site {N113} cysteine residue {C214} MODIFICATION: cysteine residue {C220} cysteine residue {C220} MODIFICATION: cysteine residue {C214}

Database Correlations

OMIM 608197 UniProt Q96LB9 Pfam PF01510

References

UniProt :accession Q96LB9