Search
peptidoglycan recognition protein (PGRP-S, PGLYRP, PGRP, SBBI68, UNQ639/PRO1269)
Function:
1) binds specifically to peptidoglycan
2) involved in innate immunity
Compartment: secreted, cytoplasmic granule
Expression:
- expressed in bone marrow > kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen, neutrophils
General
secreted protein
Properties
SIZE: MW = 22 kD
entity length = 196 aa
COMPARTMENT: cytoplasm
MOTIF: signal sequence {1-21}
cysteine residue {C30}
MODIFICATION: cysteine residue {C154}
cysteine residue {C46}
MODIFICATION: cysteine residue {C91}
cysteine residue {C67}
MODIFICATION: cysteine residue {C73}
cysteine residue {C73}
MODIFICATION: cysteine residue {C67}
cysteine residue {C91}
MODIFICATION: cysteine residue {C46}
N-glycosylation site {N112}
cysteine residue {C154}
MODIFICATION: cysteine residue {C30}
Database Correlations
OMIM 604963
UniProt O75594
Pfam PF01510
References
UniProt :accession O75594