peptidase inhibitor 15 (cysteine-rich secretory protein 8, CRISP-8, 25 kD trypsin inhibitor, p25TI, SugarCrisp, PI15, CRISP8, P25TI)

Function: 1) serine protease inhibitor 2) weak inhibitory activity against trypsin Structure: - N-glycosylated - belongs to the CRISP family Compartment: secreted Expression: - weakly expressed - expressed at low level in prostate, mammary gland, salivary gland, thyroid gland

General

glycoprotein secreted protein serine protease inhibitor; serpin

Properties

SIZE: MW = 29 kD entity length = 258 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-19} N-glycosylation site {N26} N-glycosylation site {N36} N-glycosylation site {N124} INHIBITS: serine protease

Database Correlations

OMIM 607076 UniProt O43692 Pfam PF00188

References

UniProt :accession O43692