Search
pentagastrin stimulation test (calcitonin-stimulation test)
Indications:
- useful for assessing
- C-cell hyperplasia of the thyroid
- medullary thyroid carcinoma
- multiple endocrine neoplasia-2
Procedure:
1) measurement of baseline serum calcitonin
2) injection of 5 ug/kg ideal body weight of pentagastrin
3) measurement of serum calcitonin at 0, 2, 5, 10 & 15 min
Adverse effects:
- last about 2 minutes
a) epigastric tightness
b) nausea
c) warmth
d) tingling of extremities
Related
calcitonin in serum
calcitonin; contains: katacalcin; calcitonin carboxyl-terminal peptide; CCP; PDN-21 (CALC, CALC1)
medullary thyroid carcinoma
General
provocative clinical test
special chemistry test
References
- Harrison's Principles of Internal Medicine, 13th ed.
Isselbacher et al (eds), McGraw-Hill Inc. NY,
1994, pg 2055
- Medscape
Determination of Calcitonin Levels in C-cell Disease:
Calcitonin Stimulation
http://www.medscape.com/viewarticle/586210_3