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pediatric acute-onset neuropsychiatric syndrome (PANS)
Controversial syndrome. Also see PANDAS.
Association of:
- obsessive-compulsive disorder (OCD)
- Tourette syndrome, or
- tic disorders
with non-streptococcal infection
The association is controversial.
Clinical manifestations:
- clinical symptoms of OCD observed within weeks of pharyngitis
Specific
Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infection (PANDAS)
General
syndrome
psychiatric disease; behavioral disorder
chronic mental disorder
autoimmune disease
References
- Geller B
Do PANDAS Really Exist?
NEJM Journal Watch. Jun 9, 2017
Massachusetts Medical Society
(subscription needed) http://www.jwatch.org
- Orlovska S, Vestergaard CH, Bech BH et al.
Association of streptococcal throat infection with mental
disorders: Testing key aspects of the PANDAS hypothesis in
a nationwide study.
JAMA Psychiatry 2017 May 24
PMID: 28538981