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patched domain-containing protein 3 (Patched-related protein, PTCHD3, PTR)
Function:
- may play a role in sperm development or sperm function
Structure:
- belongs to the patched family
- contains 1 SSD (sterol-sensing) domain
Compartment:
- membrane (putative)
- localizes to the midpiece of the sperm tail
Expression:
- expressed in germ cells of the testis (at protein level)
General
glycoprotein
membrane protein
testis-specific protein
Properties
SIZE: entity length = 767 aa
MW = 87 kD
COMPARTMENT: cellular membrane
MOTIF: transmembrane domain {139-159}
N-glycosylation site {N275}
N-glycosylation site {N279}
transmembrane domain {297-317}
sterol-sensing domain {383-540}
MOTIF: binding site
FOR-BINDING-OF: sterol
transmembrane domain {383-403}
transmembrane domain {423-443}
transmembrane domain {447-467}
transmembrane domain {486-506}
transmembrane domain {520-540}
transmembrane domain {603-623}
N-glycosylation site {N678}
Database Correlations
UniProt Q3KNS1
Pfam PF02460
References
UniProt :accession Q3KNS1