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parathyroid hyperplasia
Etiology:
- sporadic
- MEN1 or MEN2A
Pathology:
- usually all 4 glands enlarged, but may be asymetrical with inferior glands larger
- total weight usually 1-3 grams
Microscopic pathology:
- usually chief cell hyperplasia, may have oxyphil cell hyperplasia
- loss of adipose tissue
- usually no rim of compressed normal tissue
- may be nodular
- may have mitotic activity
Differential diagnosis:
- parathyroid adenoma
General
parathyroid disease
References
http://www.pathologyoutlines.com/parathyroid.html