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paraneoplastic antigen Ma3 (PNMA3 MA3)
Function:
Structure:
- belongs to the PNMA family
- contains 1 CCHC-type zinc finger
Compartment: nucleus, nucleolus
Alternative splicing: named isoforms=2
Expression:
- expressed at high levels in the brain & testis
- expressed at lower levels in the heart, trachea, kidney
Pathology:
- antibodies against PNMA3 are present in sera from patients with paraneoplastic neurological disorders
General
nuclear protein
zinc finger protein
Properties
SIZE: MW = 52 kD
entity length = 463 aa
COMPARTMENT: cell nucleus
MOTIF: glutamate-rich region {332-337}
MOTIF: glutamate residue (SEVERAL)
arginine-rich region {384-410}
MOTIF: arginine residue (SEVERAL)
Zn finger C2HC-type
SITE: 412-429
EFFECTOR-BOUND: Zn+2
Database Correlations
UniProt Q9UL41
References
UniProt :accession Q9UL41