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paraneoplastic antigen Ma1; neuron- & testis-specific protein 1; 37 kD neuronal protein (PNMA1, MA1)
Structure: belongs to the PNMA family
Compartment:
- nucleus, nucleolus
- in tumor cells, it is cytoplasmic
Expression:
- testis & brain specific
- in some cancer patients, it is also specifically expressed by the paraneoplastic tumor cells
Pathology:
- antibodies against PNMA1 (anti-Ma1) are present in sera from patients suffering of paraneoplastic neurologic syndromes
Related
anti-Ma antibody
General
antigen
nuclear protein
Properties
SIZE: entity length = 353 aa
MW = 40 kD
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: glutamate-rich region {335-341}
MOTIF: glutamate residue (SEVERAL)
Database Correlations
OMIM 604010
UniProt Q8ND90
Entrez Gene 9240
Kegg hsa:9240
References
- UniProt :accession Q8ND90
- OMIM :accession 604010