Papilin (PAPLN)

Structure: - belongs to the papilin family - contains 1 BPTI/Kunitz inhibitor domain - contains 3 Ig-like C2-type domain (immunoglobulin-like) - contains 1 PLAC domain - contains 5 TSP type-1 domains Compartment: secreted (putative) Alternative splicing: named isoforms=4

Properties

SIZE: entity length = 1278 aa MW = 138 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-18} TSP type-1 1 {26-80} MOTIF: cysteine residue {C38} MODIFICATION: cysteine residue {C74} cysteine residue {C42} MODIFICATION: cysteine residue {C79} cysteine residue {C53} MODIFICATION: cysteine residue {C64} cysteine residue {C64} MODIFICATION: cysteine residue {C53} cysteine residue {C74} MODIFICATION: cysteine residue {C38} cysteine residue {C79} MODIFICATION: cysteine residue {C42} TSP type-1 2 {304-361} MOTIF: cysteine residue {C316} MODIFICATION: cysteine residue {C355} cysteine residue {C320} MODIFICATION: cysteine residue {C360} cysteine residue {C331} MODIFICATION: cysteine residue {C343} cysteine residue {C343} MODIFICATION: cysteine residue {C331} cysteine residue {C355} MODIFICATION: cysteine residue {C316} cysteine residue {C360} MODIFICATION: cysteine residue {C320} TSP type-1 3 {362-421} TSP type-1 4 {423-481} TSP type-1 5 {484-539} BPTI/Kunitz inhibitor {754-804} MOTIF: cysteine residue {C754} MODIFICATION: cysteine residue {C804} cysteine residue {C763} MODIFICATION: cysteine residue {C787} cysteine residue {C779} MODIFICATION: cysteine residue {C800} cysteine residue {C787} MODIFICATION: cysteine residue {C763} cysteine residue {C800} MODIFICATION: cysteine residue {C779} cysteine residue {C804} MODIFICATION: cysteine residue {C754} immunoglobulin superfamily domain {900-995} MOTIF: cysteine residue {C931} MODIFICATION: cysteine residue {C978} cysteine residue {C978} MODIFICATION: cysteine residue {C931} immunoglobulin superfamily domain {1033-1128} MOTIF: cysteine residue {C1065} MODIFICATION: cysteine residue {C1112} cysteine residue {C1112} MODIFICATION: cysteine residue {C1065} immunoglobulin superfamily domain {1133-1218} MOTIF: cysteine residue {C1154} MODIFICATION: cysteine residue {C1202} cysteine residue {C1202} MODIFICATION: cysteine residue {C1154} PLAC {1231-1270}

Database Correlations

UniProt O95428 PFAM correlations

References

UniProt :accession O95428