pancreatic lipase complex

General

molecular complex pancreatic lipase (pancreatic triacylglycerol lipase, PNLIP)

Properties

SIZE: entity length = 465 aa MW = 51 kD COMPARTMENT: extracellular compartment SECRETED-BY: acinar cell WITHIN: pancreas SUBUNITS: pancreatic lipase MOTIF: signal sequence {1-16} cysteine residue {C20} MODIFICATION: cysteine residue {C26} cysteine residue {C26} MODIFICATION: cysteine residue {C20} cysteine residue {C107} MODIFICATION: cysteine residue {C118} cysteine residue {C118} MODIFICATION: cysteine residue {C107} serine residue {S169} N-glycosylation site {N183} aspartate residue {D193} cysteine residue {C254} MODIFICATION: cysteine residue {C278} cysteine residue {C278} MODIFICATION: cysteine residue {C254} histidine residue {H280} cysteine residue {C302} MODIFICATION: cysteine residue {C313} cysteine residue {C313} MODIFICATION: cysteine residue {C302} cysteine residue {C316} MODIFICATION: cysteine residue {C321} cysteine residue {C321} MODIFICATION: cysteine residue {C316} PLAT {355-465} MOTIF: cysteine residue {C449} MODIFICATION: cysteine residue {C465} cysteine residue {C465} MODIFICATION: cysteine residue {C449} colipase MOTIF: signal sequence {1-17} cysteine residue {C34} MODIFICATION: cysteine residue {C45} cysteine residue {C40} MODIFICATION: cysteine residue {C56} cysteine residue {C44} MODIFICATION: cysteine residue {C78} cysteine residue {C45} MODIFICATION: cysteine residue {C34} cysteine residue {C56} MODIFICATION: cysteine residue {C40} cysteine residue {C66} MODIFICATION: cysteine residue {C86} cysteine residue {C78} MODIFICATION: cysteine residue {C44} cysteine residue {C80} MODIFICATION: cysteine residue {C104} cysteine residue {C86} MODIFICATION: cysteine residue {C66} cysteine residue {C104} MODIFICATION: cysteine residue {C80}

References

Clinical Diagnosis & Management by Laboratory Methods, J.B. Henry (ed), W.B. Saunders Co., Philadelphia, PA. 1991, pg 275, 531

Components

colipase (CLPS) pancreatic lipase (pancreatic triacylglycerol lipase, PNLIP)