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PAK2 (p21-associated kinase 2) gene

A segmental duplication of chromosome 3 involving PAK2 is one of the few features distinguishing the human genome from the chimpanzee genome. [1]

Related

p21-activated kinase 2 (PAK2), S6/H4 kinase, PAK65 or gamma-PAK

General

evolutionary divergent human gene

Properties

TEMPLATE-FOR: messenger RNA TEMPLATE-FOR: p21-associated kinase 2 LOCUS: human chromosome-3 Q29 MOTIF: transcription factor binding site transcriptional start site exon intron transcriptional termination site

Database Correlations

OMIM 605022 Entrez Gene 5062

References

  1. Fortna A, Kim Y, MacLaren E, Marshall K, Hahn G, Meltesen L, Brenton M, Hink R, Burgers S, Hernandez-Boussard T, Karimpour- Fard A, Glueck D, McGavran L, Berry R, Pollack J, Sikela JM. Lineage-specific gene duplication and loss in human and great ape evolution. PLoS Biol. 2004 Jul;2(7):E207. Epub 2004 Jul 13. PMID: 15252450