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paired immunoglobulin-like type 2 receptor beta (activating receptor PILR-beta, cell surface receptor FDFACT, PILRB FDFACT, PP1551)
Function:
- paired receptors consist of highly related activating & inhibitory receptors
- role in the regulation of the immune system
- PILRB is thought to act as a cellular signaling activating receptor that associates with ITAM-bearing adapter molecules on the cell surface
Structure:
- contains 1 Ig-like V-type domain (immunoglobulin-like)
Compartment: membrane
Alternative splicing: named isoforms=3
Related
paired immunoglobulin-like type 2 receptor alpha (inhibitory receptor PILR-alpha, cell surface receptor FDF03, PILRA)
General
cell surface receptor
Properties
SIZE: MW = 26 kD
entity length = 227 aa
COMPARTMENT: plasma membrane
MOTIF: signal sequence {1-19}
immunoglobulin superfamily domain {21-143}
MOTIF: N-glycosylation site {N100}
transmembrane domain {192-212}
Database Correlations
OMIM 605342
UniProt Q9UKJ0
Pfam PF07686
References
UniProt :accession Q9UKJ0