coilin; p80 (COIL, CLN80)

Function: - component of the nuclear coiled bodies which are involved in the function or assembly/disassembly of nucleoplasmic snRNPs - during mitosis, nuclear coiled bodies disassemble, coinciding with mitotic-specific phosphorylation of p80 coilin - interacts with ANKS1B Compartment: nucleus Expression: found in all the cell types examined

General

nuclear protein phosphoprotein

Properties

SIZE: entity length = 576 aa MW = 63 kD COMPARTMENT: cell nucleus MOTIF: Thr phosphorylation site {T122} lysine-rich region {181-201} MOTIF: lysine residue (SEVERAL) Ser phosphorylation site {S271} Thr phosphorylation site {T290} Ser phosphorylation site {S301} Thr phosphorylation site {T303} threonine-rich region {310-320} MOTIF: threonine residue (SEVERAL) Ser phosphorylation site {S489}

Database Correlations

OMIM 600272 UniProt P38432 Entrez Gene 8161 Kegg hsa:8161

References

UniProt :accession P38432