p58 phospholipase-A2

PE, sn-2 arachidonyl-selective PLA2 found in cytosol of sheep platelets. Activated by Ca⁺².

General

Ca+2 binding protein mammal-specific molecule oligomerizing protein phospholipase A2; phosphatidylcholine 2-acylhydrolase (PLA2)

Properties

CONFIGURATION: dimer SIZE: MW = 58 kD COMPARTMENT: cytoplasm CELL: platelet ORGANISM: Ovis aries (sheep) MOTIF: active site MOTIF: histidine residue cysteine residue (SEVERAL) aspartate residue cysteine-rich region Ca+2-binding site

References

- Mayer RJ, Marshall LA. New insights on mammalian phospholipase A2(s); comparison of arachidonoyl-selective and -nonselective enzymes. FASEB J. 1993 Feb 1;7(2):339-48. Review. PMID: 8440410