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p51 protein
Function:
- p51A can induce apoptosis & growth suppression similar to p53
Structure:
- homologous to p53, 2 forms: p51A & p51B.
Expression:
- p51 mRNA found in skeletal muscle, placenta, mammary gland, prostate, trachea, thymus, salivary gland, uterus, heart & lung
Pathology:
- mutations were found in some epidermal carcinomas
Specific
p51 A
p51 B
General
p53 family protein
Properties
COMPARTMENT: cell nucleus
MOTIF: DNA-binding motif
References
Osada et al. Nature Medicine 4:839-43, 1998