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p51 protein

Function: - p51A can induce apoptosis & growth suppression similar to p53 Structure: - homologous to p53, 2 forms: p51A & p51B. Expression: - p51 mRNA found in skeletal muscle, placenta, mammary gland, prostate, trachea, thymus, salivary gland, uterus, heart & lung Pathology: - mutations were found in some epidermal carcinomas

Specific

p51 A p51 B

General

p53 family protein

Properties

COMPARTMENT: cell nucleus MOTIF: DNA-binding motif

References

Osada et al. Nature Medicine 4:839-43, 1998