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p33ING1
Function:
- involved in negative regulation of cell proliferation, control of cellular aging & apoptosis.
- biological effects require activity of both ING1 & p53 genes
- association between p33ING1 & p53
- activation of transcription of p21WAF1 depends on p33ING1 expression
Interactions
molecular events
General
nuclear protein
Properties
COMPARTMENT: cell nucleus
Database Correlations
OMIM 601566
MORBIDMAP 601566
References
- Garkavtsev I et al.
The candidate tumour suppressor p33ING1 cooperates with p53 in
cell growth control.
Nature 391:295-8, 1998
PMID: 9440695
Component-of
molecular complex