P2Y10 purinoceptor; P2Y purinoceptor 10; P2Y10; P2Y-like receptor (P2RY10)

Function: - putative receptor for purines - coupled to G-proteins Structure: belongs to the G-protein coupled receptor 1 family Compartment: cell membrane; multi-pass membrane protein Expression: - weakly expressed in blood leukocytes - up-regulated during promyelocytic cell differentiation along the monocytic pathway, but not during granulocytic differentiation

General

glycoprotein P2Y purinoceptor or P2Y purinergic receptor

Properties

SIZE: entity length = 339 aa MW = 39 kD COMPARTMENT: plasma membrane MOTIF: exoplasmic domain {1-39} MOTIF: N-glycosylation site {N16} N-glycosylation site {N26} transmembrane domain {40-60} cytoplasmic loop {61-68} transmembrane domain {69-89} exoplasmic loop {90-103} transmembrane domain {104-124} MOTIF: cysteine residue {C106} MODIFICATION: cysteine residue {C181} cytoplasmic loop {125-149} transmembrane domain {150-170} exoplasmic loop {171-193} MOTIF: N-glycosylation site {N178} cysteine residue {C181} MODIFICATION: cysteine residue {C106} transmembrane domain {194-214} cytoplasmic loop {215-244} transmembrane domain {245-265} exoplasmic loop {266-288} transmembrane domain {289-309} cytoplasmic domain {310-339}

Database Correlations

OMIM 300529 UniProt O00398 Pfam PF00001 Kegg hsa:2733

References

UniProt :accession O00398