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P2X6 purinoceptor; P2X purinoceptor 6; P2X6; ligand-gated ion channel purinergic receptor P2X6; P2XM; purinergic receptor P2X-like 1 (P2RX6, P2RXL1, P2X6)
Function:
- receptor for ATP
- acts as a ligand gated ion channel
Structure:
- homo- or heteropolymers (putative)
- belongs to the P2X receptor family
Compartment: membrane
Expression: expressed predominantly in skeletal muscle
General
glycoprotein
P2X purinoceptor or P2X purinergic receptor
phosphoprotein
transmembrane 2 protein
Properties
SIZE: entity length = 431 aa
MW = 48 kD
COMPARTMENT: plasma membrane
MOTIF: cytoplasmic domain {1-29}
transmembrane domain {30-50}
exoplasmic loop {51-323}
MOTIF: Tyr phosphorylation site {Y54}
N-glycosylation site {N155}
N-glycosylation site {N185}
N-glycosylation site {N200}
transmembrane domain {324-344}
cytoplasmic domain {345-431}
Database Correlations
OMIM 608077
UniProt O15547
Pfam PF00864
Kegg hsa:9127
References
- UniProt :accession O15547
- Wikipedia; Note: P2X receptor entry
http://en.wikipedia.org/wiki/P2X_receptor