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P2X5 purinoceptor; P2X purinoceptor 5; P2X5; ligand-gated ion channel purinergic receptor P2X5 (P2RX5, P2X5)
Function:
- receptor for ATP
- acts as a ligand gated ion channel
Structure:
- forms homo- or heteropolymers (putative)
- belongs to the P2X receptor family
Compartment: membrane
Alternative splicing: named isoforms=2 Name=B
Expression:
- expressed at high levels in brain & immune system
General
glycoprotein
P2X purinoceptor or P2X purinergic receptor
phosphoprotein
transmembrane 2 protein
Properties
SIZE: entity length = 421 aa
MW = 47 kD
COMPARTMENT: plasma membrane
MOTIF: cytoplasmic domain {1-30}
transmembrane domain {31-51}
exoplasmic loop {52-318}
MOTIF: Tyr phosphorylation site {Y55}
N-glycosylation site {N77}
N-glycosylation site {N202}
transmembrane domain {319-339}
cytoplasmic domain {340-421}
Database Correlations
OMIM 602836
UniProt Q93086
Pfam PF00864
Entrez Gene 5026
References
- UniProt :accession Q93086
- Wikipedia; Note: P2X receptor entry
http://en.wikipedia.org/wiki/P2X_receptor