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P2X3 purinoceptor; ligand-gated ion channel purinergic receptor P2X3; P2X purinoceptor 3 (P2RX3)
Function:
1) ligand gated ion channel
2) binds ATP
Structure:
- forms homo- or heteropolymers
- belongs to the P2X receptor family
General
glycoprotein
P2X purinoceptor or P2X purinergic receptor
transmembrane 2 protein
Properties
SIZE: MW = 44 kD
entity length = 397 aa
COMPARTMENT: cellular membrane
MOTIF: cytoplasmic domain {1-22}
transmembrane domain {23-43}
exoplasmic loop {44-317}
MOTIF: N-glycosylation site {N139}
N-glycosylation site {N170}
N-glycosylation site {N194}
N-glycosylation site {N290}
transmembrane domain {318-338}
cytoplasmic domain {339-397}
Database Correlations
OMIM 600843
UniProt P56373
Pfam PF00864
Entrez Gene 5024
Kegg hsa:5024
References
- Entrez Gene :accession 5024
- UniProt :accession P56373
- Wikipedia; Note: P2X receptor entry
http://en.wikipedia.org/wiki/P2X_receptor