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p21rho G-associated kinase [ACK] or CDC42Hs-associated kinase

Binds to GTP-bound form of p21rho-G (Cdc42Hs).

General

tyrosine kinase (protein tyrosine kinase, PTK)

Properties

SIZE: MW = 120 kD entity length = 1091 aa STATE: active state MOTIF: kinase domain SITE: N-TERMINAL MOTIF: ATP-binding site NAME: ATP-binding site Tyr phosphorylation site src homology 3 [SH3] domain allosteric site FOR-BINDING-OF: rhoG proto-oncogene protein

References

Manser et al Nature 363:364 1993