ost-alpha/ost-beta complex

Function: - acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood - efficiently transports the major species of bile acids Structure: - heterodimer composed of OSTA & OSTB

General

carrier protein (transporter) molecular complex

Properties

SUBUNITS: organic solute transporter subunit alpha MOTIF: transmembrane domain {49-69} transmembrane domain {88-108} transmembrane domain {119-139} transmembrane domain {182-202} transmembrane domain {219-239} transmembrane domain {256-276} transmembrane domain {295-317} organic solute transporter subunit beta MOTIF: transmembrane domain {36-56}

References

UniProt :accession Q86UW1

Components

organic solute transporter subunit alpha; OST-alpha (OSTA; SLC51A) organic solute transporter subunit beta; OST-beta (OSTB, SLC51B)