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osteoclast associated immunoglobulin-like receptor (osteoclast-associated receptor, hOSCAR, polymeric immunoglobulin receptor 3, PIGR3, OSCAR)
Function:
- regulator of osteoclastogenesis
Structure:
- belongs to the leukocyte receptor complex/polymeric immunogobulin receptor (PIR/LRC) family
- contains 2 Ig-like (immunoglobulin-like) domains
Compartment: membrane (putative)
Alternative splicing: named isoforms=6
General
glycoprotein
membrane protein
receptor
Properties
SIZE: entity length = 282 aa
MW = 30 kD
COMPARTMENT: cellular membrane
MOTIF: signal sequence {1-18}
immunoglobulin superfamily domain {22-116}
MOTIF: N-glycosylation site {N48}
cysteine residue {C53}
MODIFICATION: cysteine residue {C100}
cysteine residue {C100}
MODIFICATION: cysteine residue {C53}
immunoglobulin superfamily domain {126-219}
MOTIF: transmembrane domain {132-148}
Database Correlations
OMIM 606862
UniProt Q8IYS5
References
UniProt :accession Q8IYS5