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osteocalcin box
Influences tissue-specific basal levels of osteocalcin gene expression. [Not sure what is meant here. Osteocalcin is expressed only by osteoblasts. What genes other than the gene for osteocalcin contain this element?]
General
promoter element
Properties
MOTIF: CCAAT box
NUCLEOTIDE-SEQUENCE: consensus
References
- Owen TA, Bortell R, Yocum SA, Smock SL, Zhang M,
Abate C, Shalhoub V, Aronin N, Wright KL, van Wijnen AJ,
et al.
Coordinate occupancy of AP-1 sites in the vitamin D-responsive
and CCAAT box elements by Fos-Jun in the osteocalcin gene:
model for phenotype suppression of transcription.
Proc Natl Acad Sci U S A. 1990 Dec;87(24):9990-4.
PMID: 2124710