origin recognition complex subunit 1 (ORC1L, replication control protein 1, ORC1, PARC1)

Function: - component of the origin recognition complex (ORC) that binds origins of replication - role in both chromosomal replication & mating type transcriptional silencing - binds to the ARS consensus sequence of origins of replication (ATP-dependent) - interacts with CDC6 & MYST2/HBO1 Structure: - belongs to the ORC1 family - contains 1 BAH domain Compartment: nucleus

General

nuclear protein phosphoprotein protein subunit

Properties

SIZE: entity length = 861 aa MW = 97 kD COMPARTMENT: cell nucleus MOTIF: BAH {45-171} Ser phosphorylation site {S417} Ser phosphorylation site {S419} Ser phosphorylation site {S420} Ser phosphorylation site {S421} ATP-binding site NAME: ATP-binding site SITE: 534-541

Database Correlations

OMIM 601902 UniProt Q13415 PFAM correlations Kegg hsa:4998

References

UniProt :accession Q13415