orexigenic neuropeptide QRFP (P518, [contains: QRF-amide (pyroglutamylated arginine-phenylalanine-amide peptide, neuropeptide RF-amide)], QRFP)

Function: - orexigenic activity in mice - promotes aldosterone secretion by the adrenal gland when administered to rats - activity may be mediated via binding to the G-protein coupled QRFP receptor Structure: belongs to the RFamide neuropeptide family Compartment: secreted Expression: - expressed widely in brain - highest expression levels in cerebellum, medulla, pituitary, retina, vestibular nucleus, & white matter - expressed in bladder, colon, coronary artery, parathyroid gland, prostate, testis, & thyroid

Properties

SIZE: MW = 15 kD entity length = 136 aa COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-18}

References

UniProt :accession P83859