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orbital inflammation

Etiology: - dacryoadenitis (1/3) - myositis (1/3) - orbital apex syndrome - idiopathic Epidemiology: - mean age at presentation = 45 years Clinical manifestations: - pain & periorbital edema (70%) - visual impairment can occur - afferent pupillary defect - extraocular eye movement disorder may be present Differential diagnosis: - allergic reaction - orbital cellulitis (acute process) - lymphoma (chronic process) Management: - refer to ophthalmologist - glucocorticoids - 50 mg PO QD tapered to 5 mg QD over 6 weeks [2,3] - NSAIDs may be helpful - other immunosuppressives may be needed - radiation therapy has been used [2,3] - surgical debulking [3]

Related

orbital cavity (orbit)

Specific

orbital cellulitis

General

inflammation orbital disease

References

  1. Cockerham KP et al Orbital inflammation. Curr Neurol Neurosci Rep. 2003 Sep;3(5):401-9 PMID: 12914683
  2. Zborowska B et al Idiopathic orbital inflammation with extraorbital extension: case series and review Eye (2006) 20, 107-113 http://www.nature.com/eye/journal/v20/n1/full/6701780a.html
  3. Ahn Yuen SJ and Rubin PAD Idiopathic Orbital Inflammation: Distribution, Clinical Features, and Treatment Outcome Arch Ophthalmol. 2003;121:491-499 http://archopht.ama-assn.org/cgi/reprint/121/4/491.pdf