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oligodendrocyte transcription factor 3; oligo3; class B basic helix-loop-helix protein 7; bHLHB7 (OLIG3, BHLHB7)
Function:
- may determine distinct specification program of class A neurons in the dorsal part of spinal cord & suppress specification of class B neurons
Structure: contains 1 basic helix-loop-helix domain (bHLH)
Compartment: nucleus
General
basic helix loop helix (bHLH) family transcription factor
Properties
SIZE: MW = 29 kD
entity length = 272 aa
COMPARTMENT: cell nucleus
MOTIF: histidine-rich region {25-32}
MOTIF: histidine residue (SEVERAL)
coiled coil {68-89}
DNA-binding motif
SITE: 84-95
helix-loop-helix
NAME: helix-loop-helix
SITE: 96-137
FOR-BINDING-VIA: helix-loop-helix
proline-rich region
SITE: 247-250
MOTIF: proline residue (SEVERAL)
Database Correlations
UniProt Q7RTU3
Pfam PF00010
Entrez Gene 167826
References
UniProt :accession Q7RTU3