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olfactory receptor 6Q1; olfactory receptor OR11-226 (OR6Q1)
Function: odorant receptor (putative)
Structure: belongs to the G-protein coupled receptor 1 family
Compartment: cell membrane
Polymorphism:
- single nucleotide deletion at position Leu-229 in the OR6Q1 gene is more frequent in African-Americans than in non-Africans
General
glycoprotein
olfactory receptor, family 6
Properties
SIZE: entity length = 317 aa
MW = 36 kD
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-27}
MOTIF: N-glycosylation site {N7}
transmembrane domain {28-48}
cytoplasmic loop {49-56}
transmembrane domain {57-77}
exoplasmic loop {78-103}
MOTIF: N-glycosylation site {N95}
cysteine residue {C101}
MODIFICATION: cysteine residue {C193}
transmembrane domain {104-124}
cytoplasmic loop {125-143}
transmembrane domain {144-164}
exoplasmic loop {165-201}
MOTIF: cysteine residue {C193}
MODIFICATION: cysteine residue {C101}
transmembrane domain {202-221}
cytoplasmic loop {222-241}
transmembrane domain {242-262}
exoplasmic loop {263-275}
transmembrane domain {276-296}
cytoplasmic domain {297-317}
Database Correlations
UniProt Q8NGQ2
Pfam PF00001
Entrez Gene 81178
References
- UniProt :accession Q8NGQ2
- Human olfactory receptor Data exploratorium (HORDE)
http://bip.weizmann.ac.il/cgi-bin/HORDE/showgene.pl?key=symbol&value=OR6Q1