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olfactory receptor 1P1 (olfactory receptor 17-208, OR17-208, olfactory receptor OR17-9, OR1P1P, OR1P1)
Function: odorant receptor (putative)
Structure: belongs to the G-protein coupled receptor 1 family
Compartment: cell membrane
Polymorphism:
- stop codon in the gene coding for OR1P1P at position Ala-185 is responsible for functional diversity
- the stop codon is more frequent in non-Africans than in African-Americans
General
glycoprotein
olfactory receptor, family 1
Properties
SIZE: entity length = 330 aa
MW = 37 kD
COMPARTMENT: cellular membrane
MOTIF: exoplasmic domain {1-39}
MOTIF: N-glycosylation site {N19}
transmembrane domain {40-60}
cytoplasmic loop {61-71}
transmembrane domain {72-92}
exoplasmic loop {93-111}
MOTIF: cysteine residue {C111}
MODIFICATION: cysteine residue {C192}
transmembrane domain {112-132}
cytoplasmic loop {133-137}
transmembrane domain {138-158}
exoplasmic loop {159-209}
MOTIF: cysteine residue {C192}
MODIFICATION: cysteine residue {C111}
transmembrane domain {210-230}
cytoplasmic loop {231-257}
transmembrane domain {258-278}
exoplasmic loop {279-286}
transmembrane domain {287-307}
cytoplasmic domain {308-330}
Database Correlations
UniProt Q8NH06
Pfam PF00001
References
- UniProt :accession Q8NH06
- Human olfactory receptor Data exploratorium (HORDE)
http://bip.weizmann.ac.il/cgi-bin/HORDE/showgene.pl?key=symbol&value=OR1P1P