odontogenic ameloblast-associated protein (Apin, ODAM, APIN)

Function: - tooth-associated epithelia protein - probably plays a role in odontogenesis - may be incorporated in the enamel matrix at the end of mineralization process Structure: - O-glycosylated (putative) - belongs to the ODAM family Compartment: secreted (putative) Pathology: - ODAM protein is the unique constituent of calcifying epithelial odontogenic tumors

General

glycoprotein secreted protein

Properties

SIZE: entity length = 279 aa MW = 31 kD COMPARTMENT: extracellular compartment MOTIF: signal sequence {1-15} glutamine-rich region {62-206} MOTIF: glutamine residue (SEVERAL) Thr glycosylation site {T115} Thr glycosylation site {T119} Thr glycosylation site {T244} Ser glycosylation site {S249} Thr glycosylation site {T250} Thr glycosylation site {T251} Thr glycosylation site {T255} Ser glycosylation site {S256} Thr glycosylation site {T261} Thr glycosylation site {T263} Thr glycosylation site {T273} Ser glycosylation site {S275}

Database Correlations

UniProt A1E959 Kegg hsa:5495

References

UniProt :accession A1E959