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ocriplasmin ophthalmic (Jetrea)

Indications: - vitreomacular traction - macular hole Dosage: - 125 ug injections [1] - single-use glass vial containing 0.5 mg ocriplasmin in 0.2 mL solution for intravitreal injection after dilution [2] Mechanism of action: - recombinant truncated form of human plasmin

General

ocriplasmin ophthalmic agent (eyedrops)

References

  1. Stalmans P et al Enzymatic Vitreolysis with Ocriplasmin for Vitreomacular Traction and Macular Holes. N Engl J Med 2012; 367:606-615 PMID: 22894573 http://www.nejm.org/doi/full/10.1056/NEJMoa1110823 Huang J et al N Engl J Med 2012; 367:2052-2054 http://www.nejm.org/doi/full/10.1056/NEJMc1211068
  2. Jetrea http://www.rxlist.com/jetrea-drug.htm