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oclacitinib maleate (Apoquel)
Indications:
- pruritus associated with allergic dermatitis in dogs
- atopic dermatitis in dogs
Mechanism of action:
- Janus kinase inhibitor
- preferentially inhibits JAK1 over other family members
Interactions
drug adverse effects of tyrosine kinase inhibitor(s)
General
disease-modifying antirheumatic agent (DMARD)
tyrosine kinase inhibitor
Database Correlations
PUBCHEM correlations
References
- Collard WT et al
The pharmacokinetics of oclacitinib maleate, a Janus kinase
inhibitor, in the dog.
Journal of Veterinary Pharmacology and Therapeutics. 16 DEC 2013
PMID: 24330031
http://onlinelibrary.wiley.com/doi/10.1111/jvp.12087/abstract
- European Medicines Agency
Apoquel
http://www.ema.europa.eu/ema/index.jsp?curl=pages/medicines/veterinary/medicines/002688/vet_med_000280.jsp&mid=WC0b01ac058008d7a8