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nutritional disorder (malnutrition)

State of nutritional insufficiency. Etiology: - inadequate dietary intake - defective assimilation or utilization of food ingested - risk factors for poor nutritional status - alcohol or substance abuse - cognitive impairment - lack of exercise - depression & other mental health disorders - poor functional status - impecunity - limited education - immobility or lack of transportation - chronic disease - medications - poor dentition - restricted diet, poor eating habits - social isolation Pathology: 1) increased serum IgE is common 2) thymic atrophy is common 3) patients often fail to respond to delayed-type hypersensitivity skin testing Clinical manifestations: - weight loss > 15% Laboratory: 1) complete blood count - absolute lymphocyte count < 1,800/mm3 2) comprehensive metabolic panel - serum albumin < 3.5 mg/dL 3) serum cholesterol < 160 mg/dL 4) erythrocyte sedimentation rate 5) serum TSH 6) serum 25-hydroxvitamin D 6) serum prealbumin may be useful for monitoring recovery [4] Radiology: - chest X-ray Differential diagnosis: - cancer Management: - all older patients should receive a) calcium 1200 mg QD b) vitamin D 800 IU QD [4] - adequate hydration - if possible, remove disease-specific dietary restrictions - no appetite stimulants are RDA-approved to treat malnutrition - protein & energy supplements (Ensure etc) may have some benefit - enteral nutrition is preferred over parenteral nutrition [4] - see specific disorders associated nutritional deficiency - see pressure ulcer - see unintentional weight loss

Specific

appetite disorder eating disorder malabsorption mineral disorder nutritional deficiency nutritional overload overweight starvation vitamin disorder

General

metabolic disease

References

  1. nlmpubs.nlm.nih.gov/hstat/ahcpr/
  2. Saunders Manual of Medical Practice, Rakel (ed), WB Saunders, Philadelphia, 1996, pg 696-698
  3. Medical Knowledge Self Assessment Program (MKSAP) 11, American College of Physicians, Philadelphia 1998
  4. Geriatrics at your Fingertips, 13th edition, 2011 Reuben DB et al (eds) American Geriatric Society
  5. Geriatric Review Syllabus, 7th edition Parada JT et al (eds) American Geriatrics Society, 2010
  6. Nutrition support in adults National Institute for Health & Care Excellence (NICE) http://www.nice.org.uk/page.aspx?o=292900