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nuclear valosin-containing protein-like; NVLp; nuclear VCP-like protein (NVL)
Function:
- interacts with NCL/nucleolin
- phosphorylated
Structure: belongs to the AAA ATPase family
Compartment: nucleus, nucleolus
Alternative splicing: named isoforms=3
Expression:
- widely expressed
- highest levels expressed in:
- heart, placenta, skeletal muscle, pancreas, retina
General
nuclear protein
phosphoprotein
Properties
SIZE: entity length = 856 aa
MW = 95 kD
COMPARTMENT: cell nucleus
MOTIF: nucleolar localization signal {49-52}
Ser phosphorylation site {S134}
Thr phosphorylation site {T138}
Ser phosphorylation site {S159}
Ser phosphorylation site {S185}
Ser phosphorylation site {S191}
Ser phosphorylation site {S207}
Ser phosphorylation site {S211}
ATP-binding site
NAME: ATP-binding site
SITE: 305-312
ATP-binding site
NAME: ATP-binding site
SITE: 622-629
Database Correlations
OMIM 602426
UniProt O15381
Pfam PF00004
Entrez Gene 4931
Kegg hsa:4931
References
UniProt :accession O15381