nuclear ubiquitous casein & cyclin-dependent kinases substrate; P1 (NUCKS1, NUCKS, JC7)

Function: - phosphorylated by CDK1 & casein kinase - phosphorylated upon DNA damage, probably by ATM or ATR Compartment: nucleus Alternative splicing: named isoforms=2

General

nuclear protein phosphoprotein

Properties

SIZE: entity length = 243 aa MW = 27 kD COMPARTMENT: cell nucleus MOTIF: Ser phosphorylation site {S14} Ser phosphorylation site {S19} Tyr phosphorylation site {Y26} Ser phosphorylation site {S54} Ser phosphorylation site {S58} Ser phosphorylation site {S61} Ser phosphorylation site {S73} Ser phosphorylation site {S75} Ser phosphorylation site {S79} Ser phosphorylation site {S97} Ser phosphorylation site {S101} Ser phosphorylation site {S113} Ser phosphorylation site {S130} Ser phosphorylation site {S132} Ser phosphorylation site {S144} Ser phosphorylation site {S149} lysine-rich region {150-206} MOTIF: lysine residue (SEVERAL) Thr phosphorylation site {T177} Thr phosphorylation site {T179} Ser phosphorylation site {S181} Thr phosphorylation site {T202} Ser phosphorylation site {S204} Ser phosphorylation site {S214} Ser phosphorylation site {S223} Ser phosphorylation site {S229} Ser phosphorylation site {S234} Ser phosphorylation site {S240}

Database Correlations

UniProt Q9H1E3 Entrez Gene 64710 Kegg hsa:64710

References

UniProt :accession Q9H1E3