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nuclear protein Hcc-1; proliferation-associated cytokine-inducible protein CIP29; cytokine-induced protein of 29 kD (HCC1, SARNP)

Function: - may bind nucleic acids - role in transcriptional or translational control of cell growth, metabolism & carcinogenesis Structure: contains 1 SAP domain Compartment: nucleus Expression: - low expression in spleen, liver, pancreas, testis, thymus, heart & kidney - induced by erythropoietin Pathology: - increased levels are seen in hepatocellular carcinoma & pancreatic adenocarcinoma

General

nuclear protein phosphoprotein

Properties

SIZE: MW = 24 kD entity length = 210 aa COMPARTMENT: cell nucleus MOTIF: SAP {8-42} Ser phosphorylation site {S163}

Database Correlations

UniProt P82979 Pfam PF02037

References

  1. UniProt :accession P82979
  2. Atlas of Genetics and Cytogenetics in Oncology and Haematology http://atlasgeneticsoncology.org/Genes/CIP29ID42967ch12q13.html