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nuclear matrix protein 22 in urine

Indications: - screening for bladder cancer Clinical significance: - point of care proteomics test for nuclear matrix protein NMP22 - can be read in 30-50 minutes - Sensitivity: 56% (vs 16% for cytology) - Specificity: 86% (vs 99% for cytology) - Positive predicitive value: 20% (vs 55% for cytology) - Positive predicitive value: 97% (vs 95% for cytology)

Related

bladder cancer nuclear matrix protein-22

General

point of care test urine chemistry test

References

  1. Journal Watch 25(7):57, 2005 Grossman HB, Messing E, Soloway M, Tomera K, Katz G, Berger Y, Shen Y. Detection of bladder cancer using a point-of-care proteomic assay. JAMA. 2005 Feb 16;293(7):810-6. PMID: 15713770
  2. NMP22 Laboratory Test Directory ARUP: 80281