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nuclear-localized factor 1; protein (FAM148A, FAM148A, NLF1, C2CD4A)
Function:
- may be involved in inflammatory process
- may regulate cell architecture & adhesion
Structure:
- belongs to the FAM148 family
- contains 1 C2 domain
Compartment: nucleus
Expression:
- specifically expressed in endothelial cells
- up-regulated by pro-inflammatory cytokines
General
nuclear protein
Properties
SIZE: entity length = 369 aa
MW = 40 kD
COMPARTMENT: cell nucleus
MOTIF: C2 domain {270-360}
MOTIF: binding site
FOR-BINDING-OF: phospholipid
Ca+2-binding site
Database Correlations
UniProt Q8NCU7
Kegg hsa:1457
References
UniProt :accession Q8NCU7