Search
nuclear fragile X mental retardation-interacting protein 2 (FMRP-interacting protein 2, 82 kD FMRP-interacting protein, 82-FIP, proliferation-inducing gene 1 protein, NUFIP2, KIAA1321, PIG1)
Function:
- binds RNA
- interacts with FMRP
- phosphorylated upon DNA damage, probably by ATM or ATR
Compartment:
- nucleus, cytoplasm
- distribution is cell cycle-modulated
a) cytoplasmic in the G2/M phase
b) accumulates in nucleus during G1 phase
Related
nuclear fragile X mental retardation-interacting protein 1 (nuclear FMRP-interacting protein 1, NUFIP1)
General
phosphoprotein
RNA-binding protein
Properties
SIZE: MW = 76 kD
entity length = 695 aa
COMPARTMENT: cytoplasm
cell nucleus
MOTIF: histidine-rich region {12-60}
MOTIF: histidine residue (SEVERAL)
Ser phosphorylation site {S112}
Ser phosphorylation site {S212}
Ser phosphorylation site {S214}
Thr phosphorylation site {T220}
serine-rich region {373-415}
MOTIF: serine residue (SEVERAL)
Ser phosphorylation site {S572}
Ser phosphorylation site {S608}
Ser phosphorylation site {S652}
Database Correlations
UniProt Q7Z417
References
UniProt :accession Q7Z417