NF-Y protein chain C {gamma}; CAAT-box DNA-binding protein subunit C; CCAAT-binding transcription factor subunit C; transactivator HSM-1/2 (NFYC)

Function: 1) component of nuclear factor Y 2) stimulates the transcription of various genes by recognizing & binding to a CCAAT motif in promoters, for example in type 1 collagen, albumin & beta-actin genes 2) NFYB & NFYC must interact & dimerize for NFYA association & DNA binding Structure: belongs to the NFYC/HAP5 subunit family Compartment: nucleus Alternative splicing: named isoforms=3

General

nuclear protein protein subunit

Properties

SIZE: entity length = 458 aa MW = 50 kD COMPARTMENT: cell nucleus

Database Correlations

OMIM 605344 UniProt Q13952 Pfam PF00808 Kegg hsa:4802

References

UniProt :accession Q13952